Result Interpretation and Risk Assessment Considerations

Date: December 18, 2023

Amy Gaviglio, MS, CGC, a public health consultant for APHL, and Patrick Hopkins, the Newborn Screening Project Specialist at the Missouri State Public Health Laboratory created this resource. The table includes primary analytes, potential secondary analytes/ratios, potential second-tier options, potential influences for cutoffs, and potential influences for the risk assessment of the primary and secondary conditions. This table can be utilized as an additional tool to help determine relevant analyte and cutoff considerations and for continual cutoff management using disorder confirmation feedback.

Additional Resources:

Newborn Screening Analyte Interference List